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protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during an energy deficit.

53 questions · sorted by votes · page 1 of 3

58 votes 3 answers37k views
Hair started shedding at month three. Does the timing tell me whether it is the drug or the weight loss?

Started tirzepatide in February. Nothing unusual until early June, when the shedding started, and it is now substantial: handfuls in the shower, hair on the pillow,…

hair-loss
hair-loss

Telogen effluvium following rapid weight loss versus a drug-attributable effect: the timing signature that distinguishes them, protein and…

14 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
clinical-trials
clinical-trials

Reading the primary literature properly: estimands, intention-to-treat versus per-protocol, confidence intervals, absolute versus relative…

913 questions
protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
food-noise
food-noise

The reduction in intrusive, appetitive thinking about food that most people on the class describe. Its likely basis in central GLP-1R signalling,…

14 questions
asked by nadia_kowalczyk 14k · 2.0 years ago
43 votes 3 answers21k views
What protein target should I use, and is 130 g even geometrically possible inside 900 kcal?

I am 92.4 kg, female, 34, on tirzepatide 7.5 mg, and my logged intake has settled at roughly 900 kcal a day. I did not choose 900. It is what I eat when I eat until I…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
dosing-math
dosing-math

The arithmetic itself: milligrams to millilitres to insulin units, concentration after reconstitution, dose per draw, and vial-days per vial. Show…

811 questions
asked by leonid_marchuk 15k · 16 months ago
39 votes5 answers31k views
How much protein in grams do I need at 95 kg on 1,000 kcal a day?

The particulars: 95 kg · 1,000 kcal. I would like the arithmetic checked rather than the conclusion asserted. I have deliberately not used an online calculator…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by elke_brunner 14k · 2.1 years ago
39 votes5 answers23k views
How much protein in grams do I need at 81 kg on 1,200 kcal a day?

The specifics, since they change the answer: 81 kg · 1,200 kcal. I would rather understand the derivation than memorise the outcome. Two people I asked gave two…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

14 questions
asked by swab_and_wait 15k · 2.0 years ago
38 votes0 answers30k views
How much protein in grams do I need at 124 kg on 1,000 kcal a day?

Numbers first: 124 kg · 1,000 kcal. This should be a straightforward calculation and I keep getting two different answers. The numbers are arbitrary; the method is…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by swab_stopper 16k · 19 months ago
38 votes5 answers24k views
How much protein in grams do I need at 112 kg on 1,100 kcal a day?

Conditions: 112 kg · 1,100 kcal. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as well as the…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by Dr_Ilse_Vandenberg 78k · 21 months ago
37 votes 5 answers22k views
How much protein in grams do I need at 81 kg on 800 kcal a day?

The particulars: 81 kg · 800 kcal. I would like the arithmetic checked rather than the conclusion asserted. I have deliberately not used an online calculator because…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by leah_ferrers 15k · 17 months ago
36 votes 3 answers38k views
How much protein in grams do I need at 81 kg on 1,100 kcal a day?

The case in front of me: 81 kg · 1,100 kcal. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by anouk_desmet 18k · 2.2 years ago
36 votes 3 answers13k views
How much of my constipation is just eating 45% less? Working the arithmetic on residue and fluid

I want to check a hypothesis with numbers rather than argue about mechanisms. The claim I keep reading is that a large part of GLP-1 constipation is simply the…

constipation
constipation

Slowed transit as a consequence of delayed gastric emptying and reduced intake: incidence figures, fibre and hydration evidence, and why it often…

14 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
hydration
hydration

Fluid intake when thirst and intake cues are both blunted: how much of the early scale drop is fluid, how dehydration confounds a renal panel, and…

14 questions
protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
asked by lipid_panel_q 44k · 15 months ago
35 votes 2 answers24k views
How much protein in grams do I need at 88 kg on 1,100 kcal a day?

Concretely: 88 kg · 1,100 kcal. Please show the division. I want to check my own against yours. I would like the general form as well as the specific number, so I can…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by anders_vestby 17k · 15 months ago
34 votes3 answers8.6k views
What is the actual evidence behind 1.6 g/kg, and does it still apply when I am in a 40% deficit?

1.6 g/kg is quoted as though it were a physical constant. I would like to know what study it came from, what population, and whether the conditions of that study…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
clinical-trials
clinical-trials

Reading the primary literature properly: estimands, intention-to-treat versus per-protocol, confidence intervals, absolute versus relative…

913 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
resistance-training
resistance-training

Loaded training as the primary intervention for retaining lean mass in a deficit: minimum effective dose, frequency versus volume, and why…

40 questions
asked by Dr_Sara_Kuusela 46k · 8 months ago
32 votes 2 answers21k views
How much protein in grams do I need at 62 kg on 1,200 kcal a day?

The specifics, since they change the answer: 62 kg · 1,200 kcal. I would like the arithmetic checked rather than the conclusion asserted. I have deliberately not used…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by noor_alhassan 15k · 14 months ago
31 votes5 answers50k views
How much protein in grams do I need at 74 kg on 1,100 kcal a day?

Concretely: 74 kg · 1,100 kcal. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as well as the…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by eighty_six_hours 16k · 22 months ago
31 votes5 answers19k views
How much protein in grams do I need at 95 kg on 900 kcal a day?

Stated plainly: 95 kg · 900 kcal. I have worked this out and I would like someone to find the error, because I suspect there is one. My working so far, for the…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by stopper_core 50k · 17 months ago
30 votes 3 answers11k views
Does the leucine threshold matter if suppressed appetite means I only manage two meals a day?

I keep reading that muscle protein synthesis needs roughly 2.5-3 g of leucine per meal to fully trigger, and that you should distribute protein across three or four…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
resistance-training
resistance-training

Loaded training as the primary intervention for retaining lean mass in a deficit: minimum effective dose, frequency versus volume, and why…

40 questions
asked by one_ml_bac 12k · 11 months ago
29 votes5 answers44k views
How much protein in grams do I need at 88 kg on 900 kcal a day?

Setup, so nobody has to ask: 88 kg · 900 kcal. The units are where I keep going wrong, so please be explicit about them. I have sanity-checked the order of magnitude…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by ellis_thorne 17k · 17 months ago
28 votes 5 answers17k views
How much protein in grams do I need at 103 kg on 1,200 kcal a day?

Numbers first: 103 kg · 1,200 kcal. This should be a straightforward calculation and I keep getting two different answers. The numbers are arbitrary; the method is…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by forty_units 14k · 21 months ago
27 votes 3 answers29k views
How much protein in grams do I need at 74 kg on 900 kcal a day?

Stated plainly: 74 kg · 900 kcal. I have worked this out and I would like someone to find the error, because I suspect there is one. My working so far, for the…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by dermot_kiely 14k · 2.2 years ago
26 votes3 answers35k views
How much protein in grams do I need at 112 kg on 1,200 kcal a day?

What I have: 112 kg · 1,200 kcal. I can do the algebra. I am not confident about the conversion factors. If there is a standard way to lay this out, I would rather…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by rune_thoresen 14k · 20 months ago
26 votes0 answers13k views
Is hair shedding at month three telogen effluvium or something else?

It has now persisted for three weeks, which is what moved this from tolerable to worth asking about. I can parse the result. I am less sure what it licenses me to…

hair-loss
hair-loss

Telogen effluvium following rapid weight loss versus a drug-attributable effect: the timing signature that distinguishes them, protein and…

14 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
asked by wren_calloway 14k · 16 months ago
25 votes 5 answers11k views
How much protein in grams do I need at 124 kg on 1,200 kcal a day?

For reference: 124 kg · 1,200 kcal. I would rather understand the derivation than memorise the outcome. Two people I asked gave two answers that differ by a factor of…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by sample_id 17k · 12 months ago
25 votes3 answers9.4k views
How should I read a sequence of three DEXA scans over nine months of semaglutide?

I have three scans from the same centre, same technician, morning fasted each time, and I want a sanity check on how to read them, because the second scan made me cut…

dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
resistance-training
resistance-training

Loaded training as the primary intervention for retaining lean mass in a deficit: minimum effective dose, frequency versus volume, and why…

40 questions
protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
asked by vialroom 87k · 6 months ago
24 votes5 answers28k views
How much protein in grams do I need at 95 kg on 1,100 kcal a day?

Setup, so nobody has to ask: 95 kg · 1,100 kcal. I have worked this out and I would like someone to find the error, because I suspect there is one. My working so far,…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by leah_ferrers 15k · 12 months ago
24 votes5 answers13k views
How much protein in grams do I need at 103 kg on 1,400 kcal a day?

Setup, so nobody has to ask: 103 kg · 1,400 kcal. The units are where I keep going wrong, so please be explicit about them. I have sanity-checked the order of…

protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

53 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

92 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
asked by meniscus_film 34k · 6 months ago
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