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muscle-loss

Page 3 of 4 · 82 questions tagged muscle-loss.

82 questions · sorted by votes · page 3 of 4

17 votes 5 answers13k views
What fraction of loss on survodutide is lean mass according to PIONEER-4?

The case in front of me: survodutide · PIONEER-4. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
food-noise
food-noise

The reduction in intrusive, appetitive thinking about food that most people on the class describe. Its likely basis in central GLP-1R signalling,…

14 questions
asked by Dr_Ilse_Vandenberg 78k · 19 months ago
17 votes5 answers11k views
What fraction of loss on cagrilintide is lean mass according to SURMOUNT-2?

What I have: cagrilintide · SURMOUNT-2. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

14 questions
asked by swirl_dont_shake 19k · 10 months ago
16 votes 5 answers11k views
What fraction of loss on dulaglutide is lean mass according to STEP 3?

Stated plainly: dulaglutide · STEP 3. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline. I do…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by olu_babatunde 14k · 5 months ago
16 votes0 answers7.2k views
What fraction of loss on dulaglutide is lean mass according to ESSENCE?

What I am working with: dulaglutide · ESSENCE. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by mira_sundqvist 19k · 11 months ago
15 votes5 answers15k views
What fraction of loss on retatrutide is lean mass according to SURMOUNT-5?

Setup, so nobody has to ask: retatrutide · SURMOUNT-5. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by gel_pack_warm 13k · 19 months ago
15 votes 5 answers12k views
What fraction of loss on mazdutide is lean mass according to FLOW?

Details up front: mazdutide · FLOW. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
weight-regain
weight-regain

Regain after stopping or reducing: the trajectory reported in the withdrawal extensions, how much is fluid, and what the maintenance arms tell us…

14 questions
asked by teodora_ilic 15k · 7 months ago
15 votes5 answers11k views
What fraction of loss on mazdutide is lean mass according to SURMOUNT-1?

What I have: mazdutide · SURMOUNT-1. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

14 questions
asked by otto_brenner 19k · 12 months ago
15 votes 3 answers8.4k views
What fraction of loss on dulaglutide is lean mass according to PIONEER-1?

What I am working with: dulaglutide · PIONEER-1. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

14 questions
asked by ravi_pillai 16k · 10 months ago
14 votes 5 answers5.7k views
What fraction of loss on oral semaglutide is lean mass according to SURMOUNT-3?

The particulars: oral semaglutide · SURMOUNT-3. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by s_kalniete 47k · 9 days ago
13 votes4 answers9.6k views
What fraction of loss on orforglipron is lean mass according to SURPASS-3?

What I am working with: orforglipron · SURPASS-3. I have read the primary source rather than the summary, which has left me with more questions. I understand the…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by zainab_mustafa 16k · 5 months ago
12 votes 5 answers26k views
What fraction of loss on cagrilintide is lean mass according to ATTAIN-1?

Details up front: cagrilintide · ATTAIN-1. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

14 questions
asked by two_point_four 14k · 23 months ago
12 votes5 answers12k views
What fraction of loss on cagrilintide is lean mass according to STEP 8?

Numbers first: cagrilintide · STEP 8. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by haze_check 17k · 9 months ago
12 votes3 answers4.9k views
What fraction of loss on semaglutide is lean mass according to STEP 3?

Concretely: semaglutide · STEP 3. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by cold_lane 14k · 6 months ago
11 votes5 answers14k views
What fraction of loss on dulaglutide is lean mass according to TRIUMPH-1?

What I am working with: dulaglutide · TRIUMPH-1. I have read the primary source rather than the summary, which has left me with more questions. I understand the…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by shear_at_the_front 15k · 2.0 years ago
11 votes 5 answers8.6k views
What fraction of loss on ecnoglutide is lean mass according to ESSENCE?

The case in front of me: ecnoglutide · ESSENCE. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by rae_oyelowo 21k · 7 months ago
11 votes 5 answers7.8k views
What fraction of loss on mazdutide is lean mass according to STEP 3?

Numbers first: mazdutide · STEP 3. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by t_oyelaran 41k · 3 months ago
11 votes5 answers3.3k views
What fraction of loss on ecnoglutide is lean mass according to SURMOUNT-5?

The case in front of me: ecnoglutide · SURMOUNT-5. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

14 questions
asked by haze_check 17k · 5 months ago
11 votes 5 answers2.8k views
What fraction of loss on ecnoglutide is lean mass according to ATTAIN-1?

Conditions: ecnoglutide · ATTAIN-1. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by kofi_mensah 12k · 2 months ago
10 votes 5 answers5.8k views
What fraction of loss on oral semaglutide is lean mass according to SURPASS-3?

The specifics, since they change the answer: oral semaglutide · SURPASS-3. I have the document in front of me and I can read the numbers. What I cannot do is…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by mass_shift_18 14k · 3 months ago
10 votes0 answers1.7k views
Does creatinine fall simply because muscle mass fell?

I have the full paper rather than the abstract, and the supplementary appendix. I can predict the outcome but I cannot explain it, which means I will get the next…

kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
asked by ines_delacruz 16k · 5 months ago
9 votes 2 answers7.7k views
What fraction of loss on mazdutide is lean mass according to SELECT?

Numbers first: mazdutide · SELECT. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by two_point_four 14k · 22 months ago
9 votes 5 answers3k views
What fraction of loss on orforglipron is lean mass according to REDEFINE-1?

What I am working with: orforglipron · REDEFINE-1. I have read the primary source rather than the summary, which has left me with more questions. I understand the…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by nominal_ten 14k · 18 days ago
8 votes5 answers11k views
What fraction of loss on oral semaglutide is lean mass according to REDEFINE-1?

For reference: oral semaglutide · REDEFINE-1. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
asked by lukas_sedlacek 17k · 7 months ago
8 votes0 answers10k views
What fraction of loss on semaglutide is lean mass according to ATTAIN-1?

Conditions: semaglutide · ATTAIN-1. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

84 questions
weight-regain
weight-regain

Regain after stopping or reducing: the trajectory reported in the withdrawal extensions, how much is fluid, and what the maintenance arms tell us…

14 questions
asked by cold_lane 14k · 23 months ago