cardiovascular

For reference: SURPASS-2 · semaglutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable…

Details up front: PIONEER-4 · dulaglutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…

The clinician who ordered the panel was not concerned; I would still like to understand it. Please show the division. I want to check my own against yours. I would…

Numbers first: SURPASS-2 · retatrutide. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…

Numbers first: FLOW · retatrutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

Concretely: SOUL · liraglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change…

Concretely: PIONEER-4 · oral semaglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…

Concretely: ESSENCE · tirzepatide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result, which…

I have three data points across nine months, which I hope is enough to see a trend. I would like the arithmetic checked rather than the conclusion asserted. I have…

The specifics, since they change the answer: STEP 8 · survodutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them.…

Numbers first: REDEFINE-1 · retatrutide. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…

Stated plainly: SUSTAIN-6 · cagrilintide. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline. I…

Concretely: SOUL · tirzepatide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change…

What I am working with: SURMOUNT-5 · cagrilintide. I have read the primary source rather than the summary, which has left me with more questions. I understand the…

Down 18% of body weight over ten months. My triglycerides have collapsed from 3.1 to 1.1 mmol/L, which is the change everyone predicted. My LDL-C has gone from 3.4 to…

My laboratory results are from the same laboratory each time, drawn fasting, which I gather matters. Please show the division. I want to check my own against yours. I…

The specifics, since they change the answer: SUSTAIN-6 · ecnoglutide. I want to understand what this actually establishes, as opposed to what it is being used to…

My laboratory results are from the same laboratory each time, drawn fasting, which I gather matters. I want the working, not the result — I need to be able to redo it…

I keep seeing SELECT summarised as "semaglutide cuts heart attacks and strokes by 20%". I understand that 20% comes from the hazard ratio of 0.80, and I understand…

For reference: REDEFINE-1 · semaglutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am…

Concretely: PIONEER-4 · tirzepatide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result,…

For reference: STEP 3 · survodutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable…

The clinician who ordered the panel was not concerned; I would still like to understand it. The units are where I keep going wrong, so please be explicit about them.…

Setup, so nobody has to ask: SURMOUNT-1 · mazdutide. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…