Dr_Ilse_Vandenberg
Consultant endocrinologist. I read trials for a living and I will ask you for the estimand.
78kreputation
277answers
39accepted
20questions
2·4·8badges g·s·b
86tags
40Would you accept 98.8% on liraglutide from FGP without a content assay?3 answers, accepted · 59k views · purity, content-assay, vendor-vetting38How much protein in grams do I need at 112 kg on 1,100 kcal a day?5 answers · 24k views · protein-intake, nutrition, lean-mass36My ecnoglutide vial sat at minus 20 °C for twenty-one days — is testing worth it before use?5 answers, accepted · 54k views · cold-chain, peptide-stability, batch-testing34Does GGT tell me anything about hepatic fat on oral semaglutide?5 answers · 38k views · liver-enzymes, mash, bloodwork34How many freeze-thaw cycles will survodutide at 20 mg/mL tolerate?5 answers, accepted · 51k views · freeze-thaw, peptide-stability, storage34How would I detect aggregation in a cagrilintide vial without sending it to PeptideMeter?2 answers, accepted · 30k views · vial-inspection, peptide-stability, harm-reduction27Why is acetate the counter-ion on some lots and TFA on others?5 answers, accepted · 25k views · acetate-content, purity, residual-solvent22What does a 97.1% purity with a method section attached let me conclude?5 answers, accepted · 9.7k views · purity, coa, hplc22What would make you reject an HJ vial on visual inspection alone?5 answers, accepted · 16k views · vial-inspection, harm-reduction, sterility20How many units on a U-40 insulin syringe is a 2 mg dose at 6.67 mg/mL?3 answers · 9.5k views · dosing-math, insulin-syringe, reconstitution18What does STEP 8 report at the 2 mg dose level?5 answers, accepted · 8.4k views · clinical-trials, dosing-math, titration17What fraction of loss on survodutide is lean mass according to PIONEER-4?5 answers, accepted · 13k views · lean-mass, muscle-loss, dexa13What is the thermal exposure on a Chengdu to Norway lane in summer?5 answers, accepted · 21k views · cold-chain, international-shipping, storage11Does VendorInvestigate test the vial or accept the vendor’s sample?5 answers, accepted · 3.7k views · batch-testing, vendor-vetting, coa10Does aggregation of mazdutide at 2–8 °C show up as a loss of content or of purity?0 answers · 1.3k views · peptide-stability, content-assay, purity10Is 10 mg in 2.5 mL of 0.9% sodium chloride a sensible presentation for mazdutide?0 answers · 4.5k views · diluent-volume, reconstitution, dosing-math8What does a Karl Fischer water content test add for tirzepatide that a purity figure does not?5 answers · 9.5k views · content-assay, purity, coa3What does VendorInvestigate verification of Guangzhou JEEP Biotechnology actually cover?5 answers, accepted · 2.7k views · vendor-investigate, vendor-vetting, coa2What does a lot-specific certificate on an SWB report change about how I read it?5 answers · 8.7k views · coa, batch-testing, vendor-vetting1Is 2.5 mg weekly a defensible maintenance dose for oral semaglutide?5 answers, accepted · 2.1k views · maintenance-dose, clinical-trials, dosing-math