Page 4 of 15 · 360 questions tagged semaglutide.
For reference: SURMOUNT-5 · survodutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am…
Concretely: PIONEER-4 · tirzepatide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result,…
For reference: PIONEER-4 · survodutide. I would like to know whether this claim survives contact with evidence. If the answer is "nobody has tested that", I would…
Setup, so nobody has to ask: SURMOUNT-1 · mazdutide. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
What I am working with: ESSENCE · cagrilintide. This is asserted often enough that I assumed it was established, and then I went looking for the source. I have…
The particulars: liraglutide · cagrilintide. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the arguments for each and…
Details up front: SURMOUNT-4 · orforglipron. I would rather be corrected now than propagate something wrong. I am specifically not interested in a testimonial; I am…
The clinician who ordered the panel was not concerned; I would still like to understand it. This is one of those things that everyone repeats and nobody derives. This…
Concretely: ecnoglutide · mazdutide. I would like the axes of comparison first and the recommendation second. I have tried the first option and it works; the question…
The case in front of me: PIONEER-1 · tirzepatide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at…
Details up front: ATTAIN-1 · retatrutide. I would rather be corrected now than propagate something wrong. I am specifically not interested in a testimonial; I am…
For reference: ESSENCE · semaglutide. I would like to know whether this claim survives contact with evidence. If the answer is "nobody has tested that", I would like…
For reference: ATTAIN-1 · ecnoglutide. I would like to know whether this claim survives contact with evidence. If the answer is "nobody has tested that", I would like…
Conditions: REDEFINE-1 · liraglutide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result,…
The particulars: SOUL · survodutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am being…
Numbers first: PIONEER-1 · retatrutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
Details up front: SELECT · orforglipron. I am asking for verification rather than opinion, ideally with something I can read myself. It is possible the evidence…
The specifics, since they change the answer: PIONEER-4 · survodutide. I want to understand what this actually establishes, as opposed to what it is being used to…
I have read the medicinal chemistry paper and the pharmacology paper, which helped and did not finish the job. I am trying to choose between two options that are…
Every comparison I find is either a marketing graphic putting -20.9% next to -14.9% with no caveats, or a methodology piece telling me cross-trial comparison is…
The case in front of me: REDEFINE-1 · tirzepatide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the…
The case in front of me: SUSTAIN-6 · oral semaglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if…
Concretely: STEP 4 · tirzepatide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result, which…
I understand in general terms that peptides do not survive oral administration - stomach acid, proteases, and a wall of epithelium that evolved specifically to keep…