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kidney-function

Page 2 of 5 · 100 questions tagged kidney-function.

100 questions · sorted by votes · page 2 of 5

30 votes5 answers21k views
Is triglycerides a better monitoring choice than LDL-C on cagrilintide?

For reference: triglycerides · LDL-C · cagrilintide. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the arguments for…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
hormones
hormones

Endocrine changes accompanying substantial weight loss: sex hormone binding globulin, testosterone, oestradiol, cortisol and the reproductive…

14 questions
asked by u100_marks 38k · 19 months ago
29 votes5 answers35k views
Why did my magnesium move after twelve weeks on orforglipron?

Conditions: magnesium · twelve weeks · orforglipron. I have two candidate explanations and no way to distinguish them. The same procedure has worked without incident…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by p_mkhize 41k · 2.3 years ago
29 votes 5 answers31k views
Why did my GGT move after four weeks on dulaglutide?

Concretely: GGT · four weeks · dulaglutide. I think I have a problem. I am not yet sure whether it is a real problem or a measurement artefact. I want to know whether…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by oona_kekkonen 16k · 2.0 years ago
29 votes 5 answers27k views
Why did my lipase move after two weeks on survodutide?

Setup, so nobody has to ask: lipase · two weeks · survodutide. This is not behaving the way I expected and I want to understand the discrepancy before I act on it. I…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by m_haraldsen 38k · 8 months ago
28 votes3 answers9.5k views
Why did my eGFR improve by 10 points while losing 18 kg? Creatinine vs cystatin C

Eleven months, 18 kg down. My creatinine has fallen from 1.05 to 0.96 mg/dL and the reported eGFR has gone from 85 to 95. I would like to believe my kidneys have…

kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

164 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

82 questions
bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
asked by vial_five 15k · 11 months ago
27 votes0 answers33k views
Is GGT a better monitoring choice than albumin-to-creatinine ratio on dulaglutide?

The case in front of me: GGT · albumin-to-creatinine ratio · dulaglutide. I would like the axes of comparison first and the recommendation second. I have tried the…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by dead_volume 49k · 21 months ago
26 votes0 answers34k views
Why did my cystatin C move after three weeks on a GLP-1 receptor agonist?

For reference: cystatin C · three weeks · a GLP-1 receptor agonist. An unexpected observation, and I would like a differential rather than reassurance. The conditions…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by rae_oyelowo 21k · 21 months ago
26 votes 5 answers15k views
Is creatinine a better monitoring choice than cystatin C on ecnoglutide?

Stated plainly: creatinine · cystatin C · ecnoglutide. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I can obtain…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by tess_amankwah 48k · 6 months ago
25 votes5 answers14k views
Is cystatin C a better monitoring choice than creatinine on cagrilintide?

The specifics, since they change the answer: cystatin C · creatinine · cagrilintide. I am trying to choose between two options that are usually discussed as though…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by cold_lane 14k · 10 months ago
25 votes0 answers12k views
Is ALT a better monitoring choice than AST on ecnoglutide?

Setup, so nobody has to ask: ALT · AST · ecnoglutide. Both of these get recommended confidently by different people, which suggests neither is obviously right. My…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by cold_lane 14k · 8 months ago
24 votes4 answers8.3k views
Is ApoB a better monitoring choice than ferritin on oral semaglutide?

Details up front: ApoB · ferritin · oral semaglutide. I have used one of these for a while and I am considering switching, which requires a reason. What I care about…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by jonas_ekstrom 18k · 5 months ago
23 votes 5 answers16k views
Is AST a better monitoring choice than ALT on cagrilintide?

The specifics, since they change the answer: AST · ALT · cagrilintide. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by drawn_and_capped 15k · 10 months ago
23 votes 5 answers11k views
Why did my potassium move after three weeks on cagrilintide?

The specifics, since they change the answer: potassium · three weeks · cagrilintide. An unexpected observation, and I would like a differential rather than…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by mala_venkatesh 21k · 8 months ago
22 votes 4 answers6.3k views
Why did my magnesium move after twelve weeks on dulaglutide?

The case in front of me: magnesium · twelve weeks · dulaglutide. I have two candidate explanations and no way to distinguish them. The same procedure has worked…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
hormones
hormones

Endocrine changes accompanying substantial weight loss: sex hormone binding globulin, testosterone, oestradiol, cortisol and the reproductive…

14 questions
asked by area_percent 13k · 10 months ago
21 votes2 answers26k views
Is albumin-to-creatinine ratio a better monitoring choice than GGT on oral semaglutide?

Details up front: albumin-to-creatinine ratio · GGT · oral semaglutide. I have used one of these for a while and I am considering switching, which requires a reason.…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by imani_dube 19k · 18 months ago
21 votes0 answers18k views
Why did my TSH move after six weeks on liraglutide?

Details up front: TSH · six weeks · liraglutide. Before I write this off, I want to check whether it is a known failure mode. I have the lot number, the certificate…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by dmitri_savchuk 17k · 12 months ago
21 votes 5 answers17k views
Is TSH a better monitoring choice than magnesium on tirzepatide?

Numbers first: TSH · magnesium · tirzepatide. I want to know what the trade-off actually is rather than which option is fashionable. I would rather have a defensible…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by pieter_maas 22k · 8 months ago
21 votes 5 answers11k views
Why did my ALT move after eight weeks on ecnoglutide?

What I am working with: ALT · eight weeks · ecnoglutide. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by rae_oyelowo 21k · 18 months ago
21 votes0 answers9.8k views
How much fluid is enough when thirst cues are blunted?

The trend is what I care about; individual weeks are obviously noise. I would like to understand the steps well enough to explain them to someone else. I have access…

hydration
hydration

Fluid intake when thirst and intake cues are both blunted: how much of the early scale drop is fluid, how dehydration confounds a renal panel, and…

14 questions
electrolytes
electrolytes

Sodium, potassium and magnesium during reduced intake and GI losses: what the symptoms of a shortfall look like, when a panel is worth drawing,…

36 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
sleep-apnea
sleep-apnea

Obstructive sleep apnoea and the apnoea-hypopnoea index response to weight loss, including the SURMOUNT-OSA dataset and the question of whether…

14 questions
asked by Dr_Malik_Osei 37k · 10 months ago
21 votes 3 answers7.3k views
Working the FLOW renal composite into ARR and NNT - am I doing this correctly?

FLOW tested semaglutide 1.0 mg in people with type 2 diabetes and chronic kidney disease, and reported a hazard ratio of 0.76 for its composite kidney endpoint. I…

renal-outcomes
renal-outcomes

Kidney endpoints: the FLOW composite, eGFR slope as an endpoint, albuminuria regression, and why an early eGFR dip is expected rather than alarming.

14 questions
semaglutide
semaglutide

A GLP-1 receptor agonist with a fatty-acid-acylated backbone and a roughly one-week half-life, marketed for type 2 diabetes and for weight…

360 questions
clinical-trials
clinical-trials

Reading the primary literature properly: estimands, intention-to-treat versus per-protocol, confidence intervals, absolute versus relative…

913 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
asked by esther_vandeVelde 49k · 15 months ago
20 votes 5 answers36k views
Is ferritin a better monitoring choice than ApoB on dulaglutide?

Conditions: ferritin · ApoB · dulaglutide. I would like the axes of comparison first and the recommendation second. I have tried the first option and it works; the…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by cold_lane 14k · 2.2 years ago
20 votes4 answers22k views
Is HbA1c a better monitoring choice than eGFR on orforglipron?

Concretely: HbA1c · eGFR · orforglipron. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know that, so I can…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by mz_4113 99k · 18 months ago
20 votes 5 answers7.9k views
Why did my creatinine move after two weeks on ecnoglutide?

What I am working with: creatinine · two weeks · ecnoglutide. This is not behaving the way I expected and I want to understand the discrepancy before I act on it. I…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by h_villanueva 50k · 2 months ago
20 votes0 answers3.4k views
Is lipase a better monitoring choice than potassium on ecnoglutide?

Setup, so nobody has to ask: lipase · potassium · ecnoglutide. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I…

bloodwork
bloodwork

Laboratory monitoring: which panels are worth ordering, sensible intervals, reference-range versus optimal-range arguments, and how to read a…

284 questions
kidney-function
kidney-function

eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and…

100 questions
lipids
lipids

Lipid response on treatment: triglycerides, LDL-C, non-HDL-C, ApoB and Lp(a), which of them move with weight loss, and why a fasting panel drawn…

112 questions
asked by h_villanueva 50k · 2 months ago