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Does aspartimide formation dominate for tirzepatide held at 4 °C?

Asked 8 Oct 2024Modified 22 months agoViewed 20k times
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Concretely: aspartimide formation · tirzepatide · 4 °C.

I want to know whether this is a real physical effect or an artefact of how it is measured.

What prompted the question is an inconsistency between two sources I otherwise trust.

Is the standard explanation correct, and if so, what is the evidence for it?

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askedsamir_bennani13k188 Oct 2024
7For what it is worth, my own result was within half a per cent of this. – triple_agonist_q 5 months ago
6Any reason this would differ for a longer peptide? – nadia_kowalczyk 3 months ago
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