Page 14 of 15 · 360 questions tagged semaglutide.
Numbers first: ATTAIN-1 · dulaglutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…
What I have: ATTAIN-1 · orforglipron. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
For reference: tirzepatide · cagrilintide. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the arguments for each and they…
For reference: tirzepatide · liraglutide. I am trying to choose between two options that are usually discussed as though only one exists. I am not optimising for…
The specifics, since they change the answer: SURMOUNT-2 · ecnoglutide. Somebody stated this to me confidently and I would like to check it before repeating it. I…
I have the full paper rather than the abstract, and the supplementary appendix. I can predict the outcome but I cannot explain it, which means I will get the next…
The specifics, since they change the answer: PIONEER-1 · survodutide. I would like to know whether this claim survives contact with evidence. If the answer is "nobody…
This is a question about interpretation, not about whether to act — I will take action questions elsewhere. I keep seeing this stated as a fact with no explanation…
I would like to know how much of this is established and how much is a reasonable story. I want to know what the trade-off actually is rather than which option is…
The case in front of me: ESSENCE · oral semaglutide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me…
Details up front: STEP 2 · dulaglutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
The particulars: TRIUMPH-3 · survodutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
Conditions: SURMOUNT-3 · liraglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
Details up front: SURMOUNT-1 · retatrutide. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
My laboratory results are from the same laboratory each time, drawn fasting, which I gather matters. The empirical answer seems settled. The explanation does not. If…
The case in front of me: ecnoglutide · tirzepatide. I would like the axes of comparison first and the recommendation second. I have tried the first option and it…
Setup, so nobody has to ask: REDEFINE-1 · cagrilintide. This is asserted often enough that I assumed it was established, and then I went looking for the source. I…
The specifics, since they change the answer: PIONEER-4 · ecnoglutide. I want to understand what this actually establishes, as opposed to what it is being used to…
What I have: STEP 4 · orforglipron. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
The specifics, since they change the answer: SURPASS-2 · ecnoglutide. I want to understand what this actually establishes, as opposed to what it is being used to…
What I have: SOUL · orforglipron. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
The specifics, since they change the answer: SURMOUNT-OSA · ecnoglutide. Somebody stated this to me confidently and I would like to check it before repeating it. I…
For reference: liraglutide · survodutide. I am trying to choose between two options that are usually discussed as though only one exists. I am not optimising for…
Concretely: STEP 8 · oral semaglutide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at one. Has…