Conditions: 40 mg · four weeks · early satiety. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically,…
dose-escalation
Page 4 of 4 · 88 questions tagged dose-escalation.
Setup, so nobody has to ask: 20 mg · two weeks · early satiety. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me…
The particulars: 15 mg · ten weeks · vomiting. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review articles…
Numbers first: 2 mg · sixteen weeks · dizziness. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know…
Setup, so nobody has to ask: 60 mg · two weeks · nausea. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious.…
What I am working with: 20 mg · eight weeks · early satiety. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows,…
My records go back to the first dose with dates, so I can reconstruct the timeline exactly. I suspect the honest answer is that it depends, in which case I would like…
For reference: 50 mg · ten weeks · injection-site erythema. I understand the observation; what I do not understand is the mechanism behind it. I have read the two…
The particulars: 4 mg · three weeks · reflux. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried…
Concretely: 2.5 mg · twelve weeks · constipation. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the…
Conditions: 2.5 mg · four weeks · early satiety. This is one of those things that everyone repeats and nobody derives. This matters practically, not just…
The trend is what I care about; individual weeks are obviously noise. This is a planning question. I know what my options are; I do not know how to weigh them. What I…
Conditions: 40 mg · twelve weeks · nausea. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is…
The particulars: 4 mg · ten weeks · fatigue. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review articles…
What I am working with: 5 mg · eight weeks · nausea. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would…
The clinician who ordered the panel was not concerned; I would still like to understand it. This is one of those things that everyone repeats and nobody derives. This…