Page 3 of 39 · 913 questions tagged clinical-trials.
My laboratory results are from the same laboratory each time, drawn fasting, which I gather matters. I keep seeing this stated as a fact with no explanation attached,…
What I have: SURMOUNT-4 · early satiety. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
What I am working with: TRIUMPH-3 · injection-site erythema. I would like help reading this properly rather than being told what conclusion to reach. I have the full…
The particulars: SURPASS-3 · ecnoglutide. Somebody stated this to me confidently and I would like to check it before repeating it. I would accept a well-reasoned…
I have three data points across nine months, which I hope is enough to see a trend. I understand the observation; what I do not understand is the mechanism behind it.…
The particulars: STEP 5 · hair thinning · 8 mg. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that…
I am on tirzepatide 10 mg and have been flat for seven weeks. The reflex answer everywhere is "titrate up", and 12.5 and 15 mg exist, so the option is there. But I…
I am trying to calibrate how likely it is that GI side effects end up being the reason someone stops, as opposed to being an unpleasant thing they get through. The…
Setup, so nobody has to ask: hair thinning · mazdutide · PIONEER-1. I have read the primary source rather than the summary, which has left me with more questions. I…
Stated plainly: dulaglutide · SUSTAIN-6. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…
What I have: ATTAIN-1 · constipation. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
Conditions: SURMOUNT-4 · liraglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
Conditions: SUSTAIN-6 · dizziness · 60 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single…
Conditions: nausea · oral semaglutide · TRIUMPH-3. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the…
Concretely: SOUL · liraglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change…
Setup, so nobody has to ask: STEP 3 · a GLP-1 receptor agonist. I have read the primary source rather than the summary, which has left me with more questions. I…
Concretely: PIONEER-4 · oral semaglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
The particulars: oral semaglutide · 30 °C. Somebody stated this to me confidently and I would like to check it before repeating it. I would accept a well-reasoned…
Concretely: ESSENCE · tirzepatide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result, which…
Conditions: SURMOUNT-5 · oral semaglutide. I want to know whether there is evidence behind this or only repetition. I have checked the obvious registries and…
What I have: a GLP-1 receptor agonist · cagrilintide. I have used one of these for a while and I am considering switching, which requires a reason. What I care about…
I have three data points across nine months, which I hope is enough to see a trend. I would like the arithmetic checked rather than the conclusion asserted. I have…
Details up front: cagrilintide · liraglutide. I have used one of these for a while and I am considering switching, which requires a reason. What I care about is…
The specifics, since they change the answer: STEP 5 · early satiety. I have the document in front of me and I can read the numbers. What I cannot do is interpret…