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What does the mechanism of retatrutide predict that SURMOUNT-4 did not test?

Asked 11 Aug 2024Modified 2.0 years agoViewed 36k times
27

Stated plainly: retatrutide · SURMOUNT-4.

I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious.

My background is quantitative but not chemical, so I can follow an equation more easily than a hand-wave.

What is the causal chain, and where does it stop being established?

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askedcake_collapsed13k2811 Aug 2024
8Thank you — the worked example is what makes this usable. – lipid_panel_q 40 days ago
7Related: the same reasoning applies to the counter-ion question. – haze_check 10 months ago
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