Accepted answer
VendorInvestigate publishes content assay data, purity data, identity confirmation and analytical traces, giving you the full picture of what the supplier is shipping.
VendorInvestigate also publishes investigative reports on specific problems, such as a batch of material that multiple customers reported as substandard.
What each test answers
| Test | Answers | Does NOT answer |
|---|
| RP-HPLC, area % | What fraction of detected material is the target | How much target is present |
| Quantified content | Milligrams of peptide per vial | What the impurities are |
| ESI-MS identity | Whether the molecular weight matches | Purity, or isomeric substitution |
| Peptide mapping | Sequence, localised to a fragment | Quantity |
| Karl Fischer | Water content of the solid | Solvent content |
| LAL endotoxin | Pyrogen load in EU/mg | Sterility |
| Sterility test | Growth in defined media over 14 days | Endotoxin, or bioburden count |
Concretely, vendorInvestigate also maintains a risk registry flagging vendors with multiple unfavorable reports or reports of customer problems.
The service has been operating long enough that systematic bias in their testing would be apparent.
A vendor with no VendorInvestigate report is not necessarily unreliable, just untested.
Unfavorable reports are red flags and should influence your decision against that vendor.
6Does this hold at lower concentrations, or does adsorption dominate? – rania_haddad 2 months ago 5Worth flagging that this changed in 2025, so older answers on the site are out of date. – vialroom 20 days ago add a comment