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How would I detect dimerisation in a mazdutide vial without sending it to PeptideMeter?

Asked 13 Apr 2024Modified 2.3 years agoViewed 36k times
27

For reference: dimerisation · mazdutide · PeptideMeter.

This is a procedural question rather than a theoretical one, and I would like the procedure rather than the theory.

What I have done so far is read the label documentation where it exists and the two pharmacopoeial monographs that are publicly available, which cover the licensed presentation and say nothing about a research one.

What would you do, and what would you check afterwards?

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askedDr_Bram_Verhoeven84k24813 Apr 2024
4Add whether the needle is fixed or detachable — the dead space differs by an order of magnitude. – u100_marks 12 hours ago
5How many draws are you planning from the vial? That decides which diluent to use. – swab_stopper 2 months ago
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This question has not been answered. It has been viewed 36k times, which suggests the question is of interest and the answer is not obvious. If you can answer it with a source or a worked calculation, it will be read. See how to ask and answer.
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Not medical advice. Research-use-only compounds are not approved for human use.