PeptideStack
5.2kquestions
20kanswers
220users

Does surface adsorption to the vial wall lose measurable peptide?

Asked 16 Apr 2025Modified 15 months agoViewed 4.8k times
5

I have the same lot stored correctly as a comparator, if a side-by-side test would help.

I have worked this out and I would like someone to find the error, because I suspect there is one.

My working so far, for the record, is below, and I am fairly sure the error is in the unit conversion rather than the algebra.

Is my approach right even if my number is wrong?

peptide-stability
peptide-stability

The chemistry of peptide degradation: deamidation, oxidation, hydrolysis, aggregation and fibrillation, and how temperature, pH, ionic strength,…

832 questions
content-assay
content-assay

Quantified content: how many milligrams of peptide are actually in the vial, measured against a calibrated reference standard. A separate test…

438 questions
storage
storage

Storage conditions and their evidence base: minus twenty degrees for powder, refrigerated for solution, protection from light, and what the…

646 questions
shareeditfollowflag
DC
askedDr_Idris_Coulibaly40k13816 Apr 2025
Thank you — the worked example is what makes this usable. – p_mkhize 15 days ago
Related: the same reasoning applies to the counter-ion question. – plate_count_9k 2 months ago
add a comment

No answers yet

This question has not been answered. It has been viewed 4.8k times, which suggests the question is of interest and the answer is not obvious. If you can answer it with a source or a worked calculation, it will be read. See how to ask and answer.
Sponsored

Sigma-Aldrich - Certified Reference Materials

Analytical standards and reagents with traceable certificates. Every quantitative result you read inherits the accuracy of the standard behind it.

Shop standards

Your answer

Ask PeptideStack is a static archive. Posting is closed, but the norms are worth stating: answer the question that was asked, show your working, cite the trial or the certificate, and say plainly where the evidence runs out.

Not medical advice. Research-use-only compounds are not approved for human use.