Page 2 of 4 · 83 questions tagged gip-receptor.
For reference: liraglutide · SOUL. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to reason it…
Stated plainly: retatrutide · SELECT. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious. My background is…
The particulars: tirzepatide · STEP 4. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to…
Numbers first: cagrilintide · STEP 5. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how…
Conditions: survodutide · SURPASS-3. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
I can follow the basic signalling story: GLP-1 receptor is a Gs-coupled receptor, activation raises cAMP, protein kinase A does things, and in the beta cell that…
Conditions: semaglutide · SURMOUNT-2. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically, because…
Stated plainly: orforglipron · SURPASS-3. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…
Details up front: mazdutide · REDEFINE-1. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how…
For reference: oral semaglutide · PIONEER-4. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to…
The particulars: liraglutide · SURMOUNT-4. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to…
Conditions: survodutide · SELECT. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically, because it…
Numbers first: mazdutide · SURMOUNT-4. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I would…
The case in front of me: survodutide · TRIUMPH-3. This is one of those things that everyone repeats and nobody derives. This matters practically, not just…
Concretely: survodutide · SOUL. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
Details up front: mazdutide · FLOW. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how confident…
What I have: a GLP-1 receptor agonist · SELECT. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know…
Stated plainly: retatrutide · ATTAIN-1. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…
The case in front of me: semaglutide · TRIUMPH-1. This is one of those things that everyone repeats and nobody derives. This matters practically, not just…
Conditions: semaglutide · ATTAIN-1. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
Numbers first: cagrilintide · STEP 1. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I would…
What I have: mazdutide · SURPASS-2. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how confident…
What I am working with: dulaglutide · SURMOUNT-1. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would…
Stated plainly: dulaglutide · SURMOUNT-4. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…