Accepted answer
Start by asking what you are optimising for, because cost per milligram, documentation depth and lead time do not have a common winner.
Content is the more discriminating measurement than purity for supplier comparison, because purity clusters tightly among competent suppliers and content does not.
Compare documentation on a fixed checklist rather than by impression: lot specificity, method section, chromatogram availability, quantified content, water and counter-ion figures, and whether the code is on the vial.
Gradient slope, column chemistry and detection wavelength all affect the reported purity figure, which is why the method section is the part that makes results comparable.
Compare content, not purity. Purity clusters and content does not.
Confirming that a small first order plus one independent submission is the cheapest route. – tabular_nums 2 months ago 2I would add a line about writing the accept threshold down first. It is the step everyone skips. – laminar_bench 4 months ago add a comment