Page 3 of 4 · 83 questions tagged peptide-mapping.
The receptor pharmacology I can follow; the in vivo translation is where I lose the thread. The empirical answer seems settled. The explanation does not. If the…
The case in front of me: 98.4% · tirzepatide. Please show the division. I want to check my own against yours. I would like the general form as well as the specific…
Numbers first: 98.4% · dulaglutide. I can do the algebra. I am not confident about the conversion factors. If there is a standard way to lay this out, I would rather…
The specifics, since they change the answer: 98.2% · semaglutide. I would rather understand the derivation than memorise the outcome. Two people I asked gave two…
Concretely: 95.2% · liraglutide. Please show the division. I want to check my own against yours. I would like the general form as well as the specific number, so I…
I received a mapping report on tirzepatide. It states "sequence coverage: 100%" in bold at the top, and then the fragment table has exactly two entries in it.…
Setup, so nobody has to ask: 98.8% · cagrilintide. I have worked this out and I would like someone to find the error, because I suspect there is one. My working so…
What I have: 98.8% · dulaglutide. I can do the algebra. I am not confident about the conversion factors. If there is a standard way to lay this out, I would rather…
Setup, so nobody has to ask: 98.8% · a GLP-1 receptor agonist. I have worked this out and I would like someone to find the error, because I suspect there is one. My…
Setup, so nobody has to ask: 99.1% · a GLP-1 receptor agonist. I have worked this out and I would like someone to find the error, because I suspect there is one. My…
The particulars: 96.4% · ecnoglutide. I would like the arithmetic checked rather than the conclusion asserted. I have deliberately not used an online calculator…
What I have: 99.4% · orforglipron. This should be a straightforward calculation and I keep getting two different answers. The numbers are arbitrary; the method is…
The particulars: 97.6% · survodutide. I would like the arithmetic checked rather than the conclusion asserted. I have deliberately not used an online calculator…
The particulars: 99.1% · semaglutide. I would rather understand the derivation than memorise the outcome. Two people I asked gave two answers that differ by a factor…
Concretely: 96.4% · tirzepatide. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as well as the…
Concretely: 96.8% · tirzepatide. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as well as the…
Stated plainly: 99.1% · cagrilintide. The units are where I keep going wrong, so please be explicit about them. I have sanity-checked the order of magnitude and it…
The method section is present, which is unusual enough that I want to make use of it. I have read the primary source rather than the summary, which has left me with…
What I have: an HPLC purity test · aggregation · oral semaglutide. I want to know what the trade-off actually is rather than which option is fashionable. I would…
Concretely: 98.4% · liraglutide. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as well as the…
What I am working with: 95.2% · mazdutide. The units are where I keep going wrong, so please be explicit about them. I have sanity-checked the order of magnitude and…
Stated plainly: 99.1% · mazdutide. The units are where I keep going wrong, so please be explicit about them. I have sanity-checked the order of magnitude and it seems…
What I am working with: 98.4% · cagrilintide. The units are where I keep going wrong, so please be explicit about them. I have sanity-checked the order of magnitude…
For reference: 99.1% · survodutide. I would rather understand the derivation than memorise the outcome. Two people I asked gave two answers that differ by a factor of…